A tutorial for microbial genome-scale metabolic modelling:  understanding the SBML format
The systems biology markup language (SBML) is a community-driven, software and platform independent standard for expressing and exchanging systems models between different simulation and analysis software. It is defined using the unified modelling language (UML) and represented using the extensible markup language (XML)1. The SBML does not aim to produce model files that can be readily read by humans, but to provide different software with a unified medium for exchanging models. Each piece of software can then translate imported models into its own internal format1. It is important to understand the SBML for metabolic modelling and engineering because this data language has quickly become the most popular standard of model files since its first publication in 20031.